The chief scientist of the World Health Organization, Dr. Sumiya Swaminathan emphasized the necessity of obtaining the second dose of any vaccine consisting of two doses, explaining that the importance of the second dose of vaccines obtained through two doses is due to being the dose that gives an actual boost to the immune system so that the body’s response The antagonist, as well as the mesenchymal T-cell response, is very powerful.
Dr. Swaminathan added that the second dose also develops the memory response, which in turn makes the effect of the vaccine last for a long time, as when the body detects this antigen or viral protein again, it knows it needs to respond quickly.
She indicated that the two doses of the vaccine are currently given within a period of three to four weeks, but there are some data on some vaccines, including the AstraZeneca vaccine, which revealed that delaying the second dose for up to 12 weeks gives a better immune boost.
Regarding whether it is possible to obtain the first dose of a vaccine and the second from another vaccine, Dr. Swaminathan considered that science is changing and developing and the knowledge base is growing, noting that there are currently ongoing clinical trials in some countries looking at the extent of interchangeability. Between the two doses of vaccines, which means that the first dose is from one of the vaccines, while the second dose is from a different vaccine, and maybe even a different vaccine platform.
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