Friday, February 26, 2021

Pfizer Promises Covid-19 mRNA Vaccine Can Be Stored at High Temperature


KOMPAS.com- As is known, the Covid-19 vaccine developed by Pfizer with BioNTech is a superior vaccine candidate that has high efficacy.

However, one of the problems with the Pfizer vaccine facing many countries around the world is its storage system which requires a refrigerator with a very low temperature.

Promising new data have shown that the Pfizer vaccine may be able to overcome extremely cold storage requirements.

Given that new research requires how effective the injection of the corona virus vaccine based on messenger RNA (mRNA) is.

Also read: Must Stay Ice Cold, Pfizer’s Covid-19 Vaccine Distribution Will Use This Technology

Reporting from Business Insider, Monday (22/2/2021), currently Pfizer and BioNTech are seeking approval from the United States Food and Drug Administration (FDA) so that they can store the Covid-19 vaccine at a higher temperature.

New data from Pfizer shows the results of the injection vaccine they developed can be stored at temperatures between minus 13 degrees and 5 degrees Fahrenheit (minus 25 degrees to minus 5 degrees Celsius) for up to two weeks.

That is, from the data shown by Pfizer, it shows that this temperature is an alternative or complement to storing the mRNA-based Covid-19 vaccine which should be stored in a freezer at very low temperature.

Also read: WHO: Pfizer’s Covid-19 Vaccine Promises, but There is a Cold Chain Challenge

AP / Abir Sultan In this December 9, 2020 file photo, Israeli Prime Minister Benjamin Netanyahu, right, and Health Minister Yuli Edelstein, center, receive the arrival of more than 100,000 doses of the Pfizer-BioNTech Covid-19 vaccine at Ben Gurion Airport near Tel Aviv, Israel.

“We appreciate the continued collaboration with the FDA and CDC, as we work to ensure our vaccines can be shipped and stored in increasingly flexible conditions,” said Pfizer CEO Albert Bourla in a press release.

Bourla added that if approved, the new storage option will offer pharmacies and vaccination centers more flexibility in managing Pfizer’s vaccine supply.

“The data do not show any change in the efficacy of the vaccine’s ability to protect against Covid-19 disease, when stored at higher temperatures,” said Pfizer spokesman Jerica Pitts.

The Pfizer and BioNTech vaccines are the first Covid-19 vaccines approved in the United States, but every bottle of this mRNA-based coronavirus vaccine today is stored in extremely cold freezer temperatures, between minus 112 to minus 76 degrees Fahrenheit.

Also read: First Pfizer Vaccine Injection in Israel 85 Percent Effective, Study Explains

Therefore, many parties regret that, because for sure this Pfizer mRNA vaccine will be very difficult to transport and store, before it is used to vaccinate people.

One dose of Pfizer vaccine is effective at preventing infection

More than 57 million doses of the vaccine have been given in the US, according to data compiled by the Centers for Disease Control and Prevention.

In April, Dr. Anthony Fauci said that nearly everyone and anyone in the US will begin to have access to the Covid-19 vaccine.

“The majority of people can be vaccinated in mid-summer,” added Fauci.

Also read: Good News, Pfizer Covid Vaccine Effective Against Mutations of the New Corona Virus

The illustration of the Pfizer vaccine is 90 percent effective based on the observations of about 43,000 volunteers in the United States (US), only 94 people have been confirmed as Covid-19, since the second dose of the Covid-19 vaccine or placebo was administered.SHUTTERSTOCK/Blue Planet Studio The illustration of the Pfizer vaccine is 90 percent effective based on the observations of about 43,000 volunteers in the United States (US), only 94 people have been confirmed as Covid-19, since the second dose of the Covid-19 vaccine or placebo was given.

To date, there are only two approved coronavirus vaccines in the US.

In addition to the Covid-19 vaccine Pfizer and BioNTech, which are the same-based vaccine, mRNA developed by Moderna, which also recommends the use of two doses of the vaccine.

Another vaccine candidate from Johnson & Johnson released phase 3 trial data in late January, outlining the safety and efficacy of a single injection of the Covid-19 vaccine.

The injection was shown to be 66 percent effective at preventing mild and moderate infections, and 85 percent effective at preventing serious illness.

Also read: Pfizer and Moderna Test Covid-19 Vaccine on the New British Corona Virus

J&J has submitted its vaccine for emergency use authorization with the FDA, and a decision could be taken before the end of February.

Previously, data from a study conducted by Israeli researchers at the Sheba Medical Center showed that the Pfizer-BioNTech Covid-19 vaccine was very effective with just one dose.

In a study published in the journal Lancet Medical Journal, the hospital has observed that the infection rate within 15-28 days after the first dose was given, was reduced by 85 percent.

However, Pfizer-BioNTech still recommends that patients get two full doses of this mRNA vaccine.

Read also: Allergy Warning Experts for Pfizer Covid-19 Vaccine, Why?



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